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Updated Criteria for Removing Patients from COVID-19 Isolation and Designated Units

The following criteria should be used for removing patients from COVID-19 isolation and COVID-19 designated units:  

Patients with mild to moderate illness who are not severely immunocompromised: 

  • At least 10 days have passed since symptoms first appeared 
  • At least 24 hours have passed since last fever without the use of fever-reducing medications  
  • Symptoms (e.g., cough, shortness of breath) have improved. 

Patients with severe to critical illness or who are severely immunocompromised: 

  • At least 10 days and up to 20 days have passed since symptoms first appeared 
  • At least 24 hours have passed since last fever without the use of fever-reducing medications  
  • Symptoms (e.g., cough, shortness of breath) have improved. 
  • Consider consultation with infection prevention and control. 

Any patient who is 20 or more days from initial symptoms or test date regardless of symptoms or clinical status 

Definitions: 

  • Mild illness: fever, cough, or malaise without shortness of breath or abnormal CXR 
  • Moderate illness: Evidence of lower respiratory tract disease by assessment or imaging and O2 sat > 94% on room air. 
  • Severe illness:  Respiratory rate > 30, room air O2 sat <94%, (or, for patients with chronic hypoxemia, a decrease from baseline of >3%), PO2/FiO2 ratio <300, or lung infiltrates of >50% 
  • Critical illness: Respiratory failure, septic shock, or multiple organ dysfunction 
  • Severely immunocompromised: Cancer chemotherapy, < 1 yr from stem cell or organ transplant, untreated HIV/AIDS with CD4 <200, combined primary immunodeficiency disorder, prednisone > 20 mg/day x >14 days 
December 4, 2020
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